Samsom lab

People Samsom Lab

Janneke performed her PhD research on host defense to Listeria monocytogenes infections in Leiden with Ralph van Furth. After a brief postdoc on respiratory viruses at the institute for Livestock research in Lelystad she joined the lab of Georg Kraal at the VU Medical Center where she identified mechanisms of regulatory T cell induction that drive nasal and oral tolerance to harmless antigens and started her own research group. In 2005 she moved to Rotterdam to combine her fundamental mucosal tolerance research with translational research of the pathogenesis of celiac disease and inflammatory bowel disease, disorders caused by loss of mucosal tolerance to harmless food and bacterial antigens respectively. In 2013 she became head of the entire laboratory of Pediatrics.

Daniëlle finished her BSc Biomedical Sciences at Leiden University in 2017. After this she continued her studies with a research master Biomedical Sciences at Leiden University and a master Philosophy, Bioethics and Health at the VU Amsterdam. During her biomedical studies she focused on immunology and did internships in the fields of pediatric immunology and tumor-immunology. In June 2020 Daniëlle started her final master internship in the Pediatric Gastroenterology and Nutrition group of Janneke Samsom, with daily supervision by Maud Heredia. She works on the function of the regulatory molecule TIGIT, which might play a role in IBD.

Lisette graduated as a Master in Medical Biology from Leiden University in 2000. She joined the Samsom group in Amsterdam in 2000. She has set up all murine models for mucosal tolerance and intestinal inflammation and is responsible for implementing all new developments in flow cytometry. In 2005 she moved with the group to Rotterdam to continue the basic research line on intestinal tolerance. Lisette is an essential contributor to all lab projects containing murine models and/or flow cytometry and as such also trains Master/PhD students and postdocs.

Daniëlle graduated from the Utrecht University of Life Sciences and Chemistry in 2018. She joined the research group earlier for an internship from 2017 until 2018. During her internship, she worked on the role of gluten degradation and IL-10 regulation in the development of celiac disease. Daniëlle stayed with the group after graduating as a research technician. Nowadays, she is involved in patient studies for Inflammatory Bowel Disease (IBD) as well as celiac disease. Next to that, Daniëlle contributes to lab projects containing histological and immunohistochemical techniques.

Bastiaan graduated as laboratory technician with a specialization in Microbiology in 2005 at the Zadkine college in Rotterdam. Before joining the Samsom lab, Bastiaan has worked as research technician for the department of Reconstructive surgery at the ErasmusMC. In this 12 year period, Bastiaan has been involved in different research topics ranging from wound-healing, decubitus, diabetic ulcers, psoriasis as well as nerve regeneration. His field of expertise has been immuno-histochemistry and organ on a chip development in collaboration with the Technical University-Delft. Over the years, Bastiaan has trained multiple master/PhD students and post-docs. In 2019, he joined the Samsom lab, where he is part of the multidisciplinary team responsible for all patient related laboratory work involving a wide variety of laboratory techniques.

Wilco graduated as Bachelor of Applied Science in Biology and Medical Laboratory Research at Hogeschool Rotterdam. In 2007, he started his career as a research technician in the lab of Jules Meijerink at the department of Pediatric Oncology at Erasmus MC in Rotterdam, and later at Princess Máxima Center in Utrecht. During this time, Wilco designed and performed functional studies on novel genetic aberrations in T cell Acute Lymphoblastic Leukemia. Wilco joined the Samsom lab in 2021, when TIGIT and SLPI research lines prompted a growing need for hands-on experience with molecular biology techniques and sequencing strategies.